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In a recent update made to Cloudflare Workers, I made similar kinds of modifications to an internal data pipeline that reduced the number of JavaScript promises created in certain application scenarios by up to 200x. The result is several orders of magnitude improvement in performance in those applications.
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Massively parallel reporter assays across five cell types identify thousands of causal, noncoding regulatory variants among 220,000 loci, revealing diverse regulatory mechanisms shaping complex traits and disease.
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